Name: Flow Cytometry Antibody CD56-APC, Clone C5.9
- Antibody CD56-APC is a monoclonal antibody (mAb) labelled with allophycocyanine (APC) designed for use as a direct immunofluorescence reagent in the identification and enumeration of cells which express the CD56 antigen by flow cytometry (FC). This reagent must be used by flow cytometry qualified personnel.
SUMMARY AND EXPLANATION
Human lymphocytes may be classified in three main populations according to their biological function and their cell surface antigen expression: T lymphocytes, B lymphocytes and natural killer cells (NK). NK cells (CD3-CD56+) mediate cytotoxicity against certain tumors and virus-infected cells. NK-mediated cytotoxicity does not require class I or class II major histocompatibility complex (MHC) molecules to be present on the target cells. CYT-56AP mAb recognizes the CD56 antigen present on NK cells and subsets of CD3+CD4+ and CD3+CD8+ T-cells and can therefore be used in the characterization studies for immunophenotyping of lymphocytes.
Purified monoclonal CD56 antibody conjugated with allophycocyanine (APC), supplied in phosphate buffered saline with 0,09% sodium azide.
- Clone: C5.9
- Isotype: IgG2b
- Purification: Affinity chromatography.
- Amount per 1 ml vial: 200 tests (5 µl mAb per determination)
- Reagents are not considered sterile