Name: Mouse anti-Parvovirus B19 Monoclonal Antibody (Clone R92F6)
Description and aplications: Parvovirus B19 is one of the smallest viruses (20 kDa), whose nucleic acid is linear single-stranded DNA of negative polarity and without lipoprotein envelope. The viral genome encodes three proteins: the nonstructural protein NS1 and two viral capsid proteins, VP1 and VP2. The minor capsid protein VP1 has the same sequence of amino acids as VP2 plus 227 amino acids in the amino-terminus region, the VP1 unique region (VP1u). Recently, the phospholipase A2 (sPLA2) motif has been identified in VP1u in members of the Parvoviridae family, including B19, classified as an erythrovirus because of its ability to invade erythrocyte precursors in the bone marrow.
Composition: Anti-Parvovirus B19 mouse monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide
Immunogen: Amino acids 328-344 of the VP2 protein of the viral capsid
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