Name: Rabbit anti-human STAT6 Monoclonal Antibody (Clone EP325)
Description and aplications: Signal transducer and activator of transcription 6 (STAT6) is a member of the STAT family, which encompasses several cytoplasmic transcription factors that are responsible for the transmission of the activation signals induced by several cytokines and cell growth factors to the nucleus. Specifically, the STAT6 molecule is essential in the Jak/STAT transduction pathway, where it is responsible for regulating the signal that controls embryonic
development, the regulation of cell differentiation and apoptosis and certain aspects of the immune adaptive response, essentially the secretion of interleukins 3 and 4. The nuclear or cytoplasmic expression of STAT6 is a useful marker to distinguish the solitary fibrous tumor from other soft tissue neoplasms.
Composition: Anti-human STAT6 rabbit monoclonal antibody purified from culture supernatant, filtered, sterilized and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide
Immunogen: Synthetic peptide corresponding to the human STAT6.