Name: Rabbit Anti-Human T-PIT/TBX19 Polyclonal Antibody
Description and aplications: The TPIT molecule, also known as T-Box 19 or TBX19, is a gene transcription factor of the T-box gene family that is mainly involved in the regulation of embryonic development. In the case of TPIT, whose coding gene consists of 8 exons and is located in the chromosomal region 1q24.2, its expression is restricted to the two pituitary cell lines (corticotroph and melanotroph), in which it activates the POMC gene responsible for the secretion of proopiomelanocortin. This molecule, and its derivative opiomelanocortin, are the precursors of ACTH synthesis as well as of some molecules related to appetite regulation, mainly lipotropin beta.
Composition: Anti-human T-PIT/TBX19 rabbit polyclonal antibody obtained from ascitic fluid and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Immunogen: Recombinant protein corresponding to human T-PIT/TBX19.
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