(Name: Mouse anti-human BRST-3/TAG-72/CA72-4 Monoclonal Antibody (Clone 72.3
Description and applications: The Signet B72.3 monoclonal antibody recognizes TAG-72 (Tumor Associated Glycoprotein-72), a high molecular weight (220-400 kDa) glycoprotein complex.
In mature human tissue it does not produce positive reaction or if anything is very weak except for the secretory endometrium.
This antibody specifically recognizes the glycoprotein TAG-72, one oncofetal tumor-associated antigen expressed in a variety of human adenocarcinomas (84% of invasive ductal breast carcinomas, 85-90% of adenocarcinomas of the colon, pancreas, stomach , esophagus, lung, ovary and endometrium). It is not expressed in leukemias, lymphomas, sarcomas, mesotheliomas, melanomas or benign tumors.
Composition: anti-human BRST-3rabbit monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Immunogen: A membrane-enriched fraction of a breast carcinoma metastatic to the liver.