| Clone | QR106 |
|---|---|
| REF | C-C037 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human CD45 |
| Isotype | IgG |
| Species of origin | Rabbit |
CD45, also known as leucocyte common antigen, is a transmembrane protein-tyrosine phosphatase, which is found in almost all hematolymphoid cells including lymphocytes, monocytes, macrophage and granulocytes. This antibody recognizes hematolymphoid neoplasms/tumors, it is non-reactive with some lymphoid neoplasms like Hodgkin’s disease, some T-cell lymphoma and some leukemias.CD45 is an important marker in the primary tumor screening panel in order to identify hematolymphoid differentiation. Loss of CD45 in precursor B-cell neoplasmsis a negative prognostic parameter.
