Clone | QR083 |
---|---|
REF | C-A003 |
Dilution | 1:100 – 1:200 |
Immunogen | Synthetic peptide of human Arginase-1 |
Isotype | IgG |
Species of origin | Rabbit |
Arginase (ARG) is a manganese metalloenzyme that is part of the urea cycle. It catalyses the conversion of L-arginine to L-ornithine and urea. ARG-1 and ARG-2 are the two isoforms of ARG. ARG-1 is a cytosolic enzyme expressed in liver. The ARG-1 antibody is a sensitive marker of hepatic differentiation and is useful in the detection of hepatocytes in normal tissue as well as granulocytes in peripheral blood. For the identification of hepatocellular carcinoma ARG-1 is a sensitive and specific marker.