| Clone | QR075 |
|---|---|
| REF | C-M007 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human MUM1 |
| Isotype | IgG |
| Species of origin | Rabbit |
MUM1 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter as well as immunoglobulin lambda light chain enhancer, together with PU.1. It is expressed in the nuclei and cytoplasm of plasma cells, a subset of B-cells in the light zone of the germinal center, activated T-cells and a wide spectrum of related hematolymphoid neoplasms derived from these cells. This antibody is used to detect lymphoid malignancies and HodgkinÕs and Reed Sternberg cells of classic HodgkinÕs disease in combination with anti-CD30.
