| Clone | QR071 |
|---|---|
| REF | C-O001 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human Olig2 |
| Isotype | IgG |
| Species of origin | Rabbit |
Olig2 is a transcription factor involved in oligodendroglial specification. It is expressed in most glial tumors, such as oligodendrogliomas and astrocytomas, but has been not found in the non-glial tumors including neuroepithelial tumors, ependymomas, sub ependymomas, medulloblastomas, and nonneuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumor, and hemangioblastomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue.
