| Clone | QR040 |
|---|---|
| REF | C-E003 |
| Dilution | 1:50 – 1:100 |
| Immunogen | Synthetic peptide of human ERG |
| Isotype | IgG |
| Species of origin | Rabbit |
ERG, also known as ETS related gene, is a member of the ETS family of transcription factors that play important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The antibody labels endothelial cells, lymphocytes, and prostate cancer cells. Overexpression of ERG is associated with prostate cancer. Furthermore, the TMPRSS2-ERG fusion caused by translocations and interstitial deletions, is implicated in aggressive forms of prostate cancer. EWS-ERG, or EWS-Fli-1 fusion, is a characteristic of Ewing’s sarcoma.
