دسته بندی: آنتی بادیهای ایمونوهیستوشیمی
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آنتی بادیهای ایمونوهیستوشیمیآنتی بادی Cytokeratin 7 کلون OVTL 12/30 برند Patho Sage
Specification:
This antibody recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Immunogen:
OTN 11, ovarian carcinoma cell line
Presentation:
Bioreactor concentrate with 0.05% Azide
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آنتی بادیهای ایمونوهیستوشیمیآنتی بادی PAX8 کلون PAX8/1492 برند Patho Sage
Specification:
PAX8 antibody recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but normal ovarian surface epithelial cells. PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Immunogen:
Recombinant human PAX8 protein
Presentation:
Purified antibody from bioreactor concentrate