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برچسب: فلوسایتومتری

نمایش دادن همه 19 نتیجه

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  • 7-AAD Viability Staining Solution
    آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری 7-AAD Viability Staining Solution

    امتیاز 0 از 5

    7-AAD Viability Staining Solution

    Company: BioLegend

    Catalog: 420403

     Size: 200 tests

    Storage & Handling: Protect from light. Store between 2°C and 8°C

    Description:

    7-AAD (7-amino-actinomycin D) has a high DNA binding constant and is efficiently excluded by intact cells. It is useful for DNA analysis and dead cell discrimination during flow cytometric analysis. When excited by 488 laser light, 7- AAD fluorescence is detected in the far red range of the spectrum (650 nm longpass filter).

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری APC anti-human CD3 Antibody

    امتیاز 0 از 5

    APC anti-human CD3

    Company: BioLegend

    Catalog : 300311, 300312

    Size: 25 tests  / 100 tests

     Clone: HIT3a

     Isotype : Mouse IgG2a, κ

     Reactivity: Human

    Description:

    CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor T-cell heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری APC anti-mouse CD8a Antibody

    امتیاز 0 از 5

    APC anti-mouse CD8a Antibody

    Company:BioLegend

    Catalog Number: 100711

    Size : 25 µg

    Clone : 53-6.7

    Isotype : Rat IgG2a, κ

    Reactivity : Mouse

    Description :

    CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigenpresenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-human CD2 Antibody

    امتیاز 0 از 5

    FITC anti-human CD2 Antibody

    Company:BioLegend

    Catalog : 300206

    Size : 100 tests

    Clone :  RPA-2.10

    Isotype  : Mouse IgG1, κ

    Reactivity  : Human, African Green, Baboon, Capuchin Monkey, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus, Swine (Pig, Porcine)

    Description

     CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-human CD16 Antibody

    امتیاز 0 از 5

    FITC anti-human CD16 Antibody

    Company:BioLegend

    Clone: B73.1

    Isotype: Mouse IgG1, κ

    Reactivity: Human

    Cat Number: 360716

    Antibody Type: Monoclonal

    Description:

    CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-human CD33 Antibody

    امتیاز 0 از 5

    FITC anti-human CD33 Antibody

    Company:BioLegend

    Catalog : 303303

    Size: 25 tests

    Isotype: Mouse IgG1, κ

    Reactivity: Human, Cross-Reactivity : Chimpanzee

    Description:

    CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate/lectin binding activity.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-mouse CD4 Antibody

    امتیاز 0 از 5

    FITC anti-mouse CD4 Antibody

    Company:BioLegend

    Catalog Number : 100405

    Size : 50 µg

    Clone : GK1.5

    Isotype: Rat IgG2b, κ

    Reactivity : Mouse

    Description :

    CD4 is a 55 kD protein also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-mouse CD8a Antibody

    امتیاز 0 از 5

    FITC anti-mouse CD8a Antibody

    Company:BioLegend

    Catalog Number : 100705

    Size : 50 µg

    Clone : 53-6.7

    Isotype : Rat IgG2a, κ

    Reactivity : Mouse

    Description :

    CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigenpresenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-mouse CD49b (pan-NK cells) Antibody

    امتیاز 0 از 5

    FITC anti-mouse CD49b (pan-NK cells) Antibody

    Company:BioLegend

    Catalog Number : 108905

    Size : 50 µg

    Clone : DX5

    Isotype : Rat IgM, κ

    Reactivity : Mouse

    Description :

    DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α integrin, VLA-2 α chain, and integrin α chain. CD49b non-covalently associates with CD29 (β integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

  • biolegend
    آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC anti-mouse/human CD11b Antibody

    امتیاز 0 از 5

    FITC anti-mouse/human CD11b Antibody

    Company:BioLegend

    Catalog Number : 101205

    Size : 50 µg

    Clone : M1/70

    Isotype : Rat IgG2b, κ

    Reactivity : Mouse, Human, Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Rabbit (Lapine)

    Description :

    CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری FITC F(ab’)2 Goat anti-human IgG Fcγ Antibody

    امتیاز 0 از 5

    FITC F(ab’)2 Goat anti-human IgG Fcγ Antibody

    Company:BioLegend

    Catalog Number: 398006

    Size : 100 µg

    Clone : Poly23980

    Isotype : Goat Polyclonal Ig

    Reactivity : Human

    Description :

    gG Fc is a homodimer that is composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE anti-human CD79a (Igα) Antibody

    امتیاز 0 از 5

    PE anti-human CD79a (Igα) Antibody

    Company:BioLegend

    Catalog Number : 333503

    Size: 25 tests

    Clone : HM47

    Isotype : Mouse IgG1, κ

    Reactivity: Human

    Description:

    CD79a is a 47 kD type I integral membrane protein, also known as mb-1 or Iga. It is a member of the Ig superfamily and disulphide-associated with CD79b (B29). The interaction of CD79a/CD79b heterodimer with B cell suface Ig forms B cell antigen complex. CD79a is expressed in B cells from early pre-B to plasma cell stage. It has been shown that CD79a is also weakly expressed in some precursors of T- and myeloid cells. CD79 mediates the transport of IgM to B cell surface and transduces signals initiated by BCR aggregation.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE anti-mouse CD366 (Tim-3) Antibody

    امتیاز 0 از 5

    PE anti-mouse CD366 (Tim-3) Antibody

    Company:BioLegend

    Catalog Number : 119703

    Size : 50 µg

    Clone : RMT3-23

    Isotype : Rat IgG2a, κ

    Reactivity : Mouse

    Description :

    CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE anti-mouse CD107a (LAMP-1) Antibody

    امتیاز 0 از 5
  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE anti-mouse Ly-6G/Ly-6C (Gr-1) Antibody

    امتیاز 0 از 5

    PE anti-mouse Ly-6G/Ly-6C (Gr-1) Antibody

    Company:BioLegend

    Catalog Number : 108407

    Size : 50 µg

    Clone : RB6-8C5

    Isotype : Rat IgG2b, κ

    Reactivity : Mouse

    Description :

    Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

  • biolegend
    آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE anti-TCF1 (TCF7) Antibody

    امتیاز 0 از 5

    PE anti-TCF1 (TCF7) Antibody

    Company:BioLegend

    Catalog Number : 655208

    Size : 100 tests

    Clone : 7F11A10

    Isotype : Mouse IgG1, κ

    Reactivity : Human

    Description :

    TCF1 is the first identified member of the T-cell-specific transcription factor family. It plays an important role in T cell development and differentiation. TCF1 is inactivated by association with the transcriptional repressor TLE proteins. During Wnt signaling, the transcriptional coactivator CTNNB1 accumulates and, in turn, replaces the transcriptional repressor associated with TCF1. Interaction with CTNNB1 results in transactivation of TCF1 target genes. Deletion of TCF1 causes massive apoptosis of double positive thymocyte, suggesting that TCF1 is required for thymocyte survival during T cell development. In addition to its function in thymus, TCF1 promotes T cell differentiation to Th2 cells in the periphery through transcriptional activation of GATA3.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE/Cyanine5 anti-human CD3 Antibody

    امتیاز 0 از 5

    PE/Cyanine5 anti-human CD3 Antibody

    Company:BioLegend

    Clone: HIT3a

    Isotype: Mouse IgG2a, κ

    Cat Number: 300309

    Reactivity: Human

    Antibody Type: Monoclonal

    Description:

    CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PE/Cyanine5 anti-human CD19 Antibody

    امتیاز 0 از 5

    PE/Cyanine5 anti-human CD19 Antibody

    Company:BioLegend

    Catalog Numbeer: 302209

    Size : 25 tests

    Clone : HIB19

    Isotype: Mouse IgG1, κ

    Reactivity: Human, Chimpanzee, Rhesus

    Description :

    CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR coreceptor.

  • آنتی بادیهای فلوسایتومتری

    آنتی بادی فلوسایتومتری PerCP/Cyanine5.5 anti-mouse CD279 (PD-1) Antibody

    امتیاز 0 از 5

    PerCP/Cyanine5.5 anti-mouse CD279 (PD-1) Antibody

    Company:BioLegend

    Catalog Number : 135207

    Size : 25 µg

    Clone : 29F.1A12

    Isotype : Rat IgG2a, κ

    Reactivity : Mouse

    Description :

    CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

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