| Clone | QR109 |
|---|---|
| REF | C-C044 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human CD30 |
| Isotype | IgG |
| Species of origin | Rabbit |
CD30 is a cell membrane protein, that regulates activation of NF-kappa B and apoptosis. It is expressed by Reed-Sternberg cells of classical Hodgkin’s disease. CD30 is a member of the tumor necrosis factor receptor (TNF-R)superfamily, which comprises more than 10 different members. CD30 has an extra cytoplasmic domain, transmembrane region, and a cytoplasmic domain. The protein is heavily glycosylated within the Golgi apparatus(120 kDa). This antibody detects Hodgkin‘s lymphoma, anaplastic large cell lymphomas, primary cutaneousCD30+ T-cell lymphoproliferative disorders and embryonal carcinomas.
