Clone | QR086 |
---|---|
REF | C-F001 |
Dilution | 1:100 – 1:200 |
Immunogen | Synthetic peptide of human Factor XIIIa |
Isotype | IgG |
Species of origin | Rabbit |
Factor XIII is activated in the blood coagulation cascade by thrombin and calcium to a transglutaminase stabilizing the fibrin clot. This antibody detects the coagulation factor XIIIa subunit. Defects in factor XIIIa cause factor XIII subunit a deficiency an autosomal recessive disorder characterized by a lifelong bleeding tendency, defective wound healing, and habitual abortion.