| Clone | QR102 |
|---|---|
| REF | C-C038 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human CD138 |
| Isotype | IgG |
| Species of origin | Rabbit |
CD138, also known as syndecan-1, is a transmembrane heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family, which mediate cell binding, cell signaling and cytoskeletal organization. The syndecan 1 protein participates in cell proliferation, cell migration and cell-matrix interactions. This antibody is a useful marker for labeling normal mature plasma cells and early pre B-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms, the expression of CD138 is found in various types of carcinomas.
