| Clone | QR093 |
|---|---|
| REF | C-C019 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human CD34 |
| Isotype | IgG |
| Species of origin | Rabbit |
CD34 is a single-pass type I transmembrane glycoprotein and functions as a cell to cell adhesion factor. It is expressed on endothelial cells, hematopoietic progenitor cells, fibroblasts and other stromal components. The protein is thought to mediate the stem cell attachment to the bone marrow, ECM or stromal cells. CD34 is a known marker for quantifying and purifying hematopoietic progenitor cells. In identification of tumors with endothelial or lymphoid differentiation CD34 plays a useful role. It also supports in detection of gastrointestinal stromal tumors.
