| Clone | QR056 |
|---|---|
| REF | C-P020 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human PAX5 |
| Isotype | IgG |
| Species of origin | Rabbit |
PAX5 is a transcription factor and important regulator in early development. Alterations in the expression of PAX5 gene are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
