| Clone | QR016 |
|---|---|
| REF | C-P008 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human PAX8 |
| Isotype | IgG |
| Species of origin | Rabbit |
PAX8 is a member of the PAX family (Paired Box) of transcription factors. It is vital for organogenesis during the embryonic development of the kidneys, Müller organs and thyroid. Due to the restrictive expression in normal tissues, PAX8 is a sensitive and specific marker for primary tumors as well as for metastatic tumors from the above-mentioned organs and tissues. PAX8 is expressed in thyroid carcinoma (~90%), endometrial carcinoma (84-98%), ovarian carcinoma (71 99%) and renal cell carcinoma (~90%).
