Clone | QR022 |
---|---|
REF | C-C007 |
Dilution | – |
Immunogen | – |
Isotype | – |
Species of origin | – |
Cyclin D1 plays an important role in control of cell cycle and cell proliferation by regulating cyclin-dependentkinases. Cyclin D1 is a proto-oncogen. Overexpression and nuclear accumulation is associated with various cancers including breast, colon and prostate cancer, melanoma and lymphoma. Cyclin D1 may be used to differentiate mantle cell lymphoma from other B cell lymphoma.