Name: Flow Cytometry Antibody CD138-Pacific Blue™, Clone B-A38
- Antibody CD138 reagent is a monoclonal antibody (mAb) conjugated with different fluorochromes (see table) and designed for flow cytometry use as a direct immunofluorescence reagent in the identification and enumeration of human CD138 antigen-expressing cells. This reagent must be used by flow cytometry qualified personal.
SUMMARY AND EXPLANATION
The mAb Anti-CD138 reacts with human CD138, syndecan-1, a 20-22 kDa protein that binds to interstitial extracellular matrix molecules. CD138 is predominantly expressed on epithelial cells and B lymphocytes at specific stages in their differentiation: precursor B cells in the bone marrow and antibody-secreting cells, including plasma cells but not mature peripheral B cell. The simultaneous assessment of the expression of CD38 and CD138 represents the best combination of markers for the identification of plasma cells.
REAGENT COMPOSITION
The purified mAb CD138 conjugated with different fluorochromes (see table above) is supplied in phosphate-buffered saline (PBS) containing 1% (m/v) BSA and 0,09% (m/v) sodium azide.
- Clone: B-A38.
- Isotype: Mouse / IgG1.
- Reagent is considered non-sterile.
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