Name: Flow Cytometry Antibody CD138-PECy5, Clone B-A38
- Antibody CD138-PECy5 is a monoclonal antibody (mAb) labelled with R-phycoerythrin-cyanine 5 (PECy5) designed for flow cytometry (FC) use as a direct immunofluorescence reagent in the identification and enumeration of CD138 antigenexpressing cells.
SUMMARY AND EXPLANATION
Human lymphocytes may be classified in three main populations according to their biological function and their cell surface antigen expression: T lymphocytes, B lymphocytes and natural killer cells (NK). B lymphocytes are the producers of antibodies and mediate humoral immunity particularly effective against toxins, whole bacteria, and free viruses. The CYT-138C4 mAb reacts with CD138, syndecan-1, a 20-22 kDa protein that binds to interstitial extracellular matrix molecules. CD138 is predominantly expressed on epithelial cells and B lymphocytes at specific stages in their differentiation: precursor B cells in the bone marrow and antibody-secreting cells, including plasma cells but not mature peripheral B cell.
The purified monoclonal CD138 Antibody conjugated with R-phycoerythrin-cyanine 5 (PECy5) is supplied in phosphatebuffered saline (PBS) containing 0,09% sodium azide.
- Clone: B-A38.
- Isotype: IgG1.
- Amount per 1 mL vial: 200 tests (5 µL mAb per determination).
- Reagent is considered non-sterile.