Name: CD54/ICAM-1 Monoclonal Antibody Clone 23G12
Description and applications: ICAM-1 (intercellular adhesion molecule) has 7 potential N-linked glycosylation sites. It is a single
chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1).
Composition: Anti-human CD54/ICAM-1 mouse monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Immunogen:Recombinant protein encoding part of the external domain of human CD54.