آنتی‌ بادی Estrogen Receptor (SP1)

Name: Rabbit Anti-Human Estrogen Receptor (ER) Monoclonal Antibody clone SP1

Description and aplications: This rabbit monoclonal antibody (clone SP1) specifically reacts with the human alpha isoform of the estrogen receptors not having been tested in other species as mouse, rat and hamsters were it shows reactivity.This antibody is useful for immunohistochemical identification of estrogen receptor in normal and neoplastic cells estrogen dependent. However, the description of various types of benign and malignant neoplasms positive for estrogen receptors as meningiomas, lung and stomach adenocarcinoma, and above all in breast cancer, the amount of estrogen receptors expression in the tissue is an important parameter in predicting the prognosis of the disease and its response to endocrine therapy.

Presentation: ready-to-use

Composition: anti-ER rabbit monoclonal antibody obtained from supernatant culture and prediluted in a tris buffered solution pH 7.4 containing 0.375mM sodium azide solution as bacteriostatic and bactericidal.

Immunogen: Synthetic peptide derived from the C-terminus of human estrogen receptor alpha

Species reactivity: In vitro diagnostics in humans. Not tested in other species