Name: Herpes Simplex Virus I+II Antibody (Polyclonal)
Description and applications: Herpes viruses type 1 and 2 (HSV-1 and HSV-2) belong to the family of herpesviridae. Its genome consists of a linear double molecule of DNA of approximately 100,000 kD encoding more than 75 gene products. The homology between the genomic structure of HSV-1 and 2 is ofapproximately 50%, so that while most of the polypeptides encoded for each type of herpes virus have a similar structure and are antigenically related, there are numerous proteins of both viruses that condition particular responses of the host’s immune system and allow its serological and immunohistochemical differentiation. The monoclonal antibody described herein reacts with the herpes simplex virus type 2 and is useful in detecting HSV II induced lesions. At high concentrations, cross-reactivity has been observed against some strains of the varicella zoster virus. The antibody does not react against CMV or Epstein- Barr virus cultures.
Composition: anti-human Herpes Simplex Virus I+II rabbit polyclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
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