Specification:
B-A38, anti CD138, recognizes the 30.5 kD syndecan-1 proteoglycan expressed on human plasma cells, endothelial cells and fibroblasts. It is expressed on epithelial and endothelial cells and on cells of B lymphocyte lineage at discrete differentiation stages. Syndecan-1 is expressed on precursor B cells, is lost before maturation and entry into the circulation, and is re expressed upon plasma cells. It detects also thymocytes, activated T-cells, basophils, natural killer cells, and monocytes. B-A38, anti CD138, detects 70-100% of multiple myeloma cells and B cell chronic lymphocytic leukemia.
Presentation:
1 ml of 0.1 mg of purified IgG in of 0.01 M sodium phosphate, 0.15M NaCl; pH 7.3,0.2 % BSA,0.09% sodium azide.
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