آنتی بادی CD21 کلون CR2/2754 برند Patho Sage

Specification:

Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and t lymphocytes. In B-cells ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-Cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d. C3dg and IC3b complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81, and Leu13 to form a large signal-transduction complex involved in B cell activation.

Immunogen:

Recombinant fragment (around aa142-240) of human CR2 (CD21) protein (exact sequence is proprietary)

Presentation:

Bioreactor Concentrate with 0.05% BSA and 0.05% Azide