Specification:
MIC-2 (CD99) antigen is present on the cell membrane of Ewing’s Sarcoma and primitive peripheral neuroectodermal tumors (PNET). It is also present on some bone marrow, lymph nodes spleen, cortical thymocytes, granulosa cells of the ovary, most beta cells, CNS ependymal cells, Sertoli’s cells of the testis and endothelial cells. MIC-2 (CD99) has also been identified in lymphoblastic lymphoma, rhabdomyosarcoma, mesenchymal chondrosarcoma, and thymoma. CD99 is expressed in most pancreatic endocrine tumors and loss of CD99 expression is associated with poor prognosis in these tumors.
Presentation:
Anti-CD99 is a rabbit monoclonal from tissue culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with protein base, and preserved with sodium azide.
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