آنتی بادی ESA (Epithelial Specific Antigen) کلون MOC-31 برند Patho Sage

Specification:

SCLC-CD2; epithelial antigen, EGP-2. MOC-31 reacts with an epithelial antigen of 40kD present on most normal and malignant epithelia.MOC-31 has been assigned to a group of antibodies known as SCLC-Cluster 2 which react with an epithelial antigen determined at the Second International Workshop on Small Cell Lung Cancer (SCLC)Antigens. In normal tissues, clone MOC-31 reacts with glands and hair shafts in skin, pancreatic exocrine and endocrine glands, epithelia of the digestive and respiratory tract, including sero-mucous glands. MOC-31 stains epithelia of kidney, endometrium, breast, liver, prostate, pancreatic acini, slets and ducts. No reactivity is observed with adrenal, ovary, brain, peripheral nerve, ganglion cells, peripheral blood and bone marrow. Lung-derived tumours such as squamous cell carcinomas, adenomas, small cell lung carcinomas, carcinoids, adenocystic carcinomas, carcinosarcoma, mucoepidermal carcinoma and pleomorphic adenoma stain positively with MOC-31.Also,colon adenocarcinoma, gastric adenocarcinoma, esophagealgastric adenocarcinoma, some bladder transitional cell carcinomas, prostate adenocarcinoma, testicular yolk tumours, uterine adenomatoid tumours, ovary mucinous/endometrial cancers, serous carcinoma of the ovary, some breast carcinomas, thyroid papillary carcinoma and thyroid medullary carcinomas may be positive.

Immunogen:

Neuraminidase treated cells from a variant small cell lung carcinoma cell line (GLS-1)

Presentation:

Bioreactor Concentrate with 0.05% Azide