.(Name: Vimentin Antibody (Clone SP20
Description and applications: Vimentin is the main intermediate filament protein in mesenchymal cells and is therefore of value in the differential diagnosis of undifferentiated neoplasms. In mesenchymal tumors, vimentin expression is practically the rule, though, it must not forget that there are epithelial tumors that coexpressed Vimentin and cytokeratins, such as thyroid gland carcinomas, pleomorphic adenomas salivary of the salivary glands and some renal carcinomas. Furthermore, by the universal staining the anti-vimentin antibody in the blood vessels and lymphoid tissue, they are considered the best internal control to assess the results of immunostaining.
Composition: anti-human Vimentin, rabbit monoclonal antibody purified from culture supernatant, prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Immunogen: Recombinant protein encoding human vimentin.