| Clone | QR062 |
|---|---|
| REF | C-B001 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human Bcl2 |
| Isotype | IgG |
| Species of origin | Rabbit |
Bcl2 (B-cell lymphoma 2) plays an important role in regulation of apoptosis. It is expressed in different cells and tissues. Overexpression due to chromosomal translocation, gene amplification, increased gene transcription and/or altered post-translational processing is found in many cancer types. These include B-cell malignancies, such as B-cell lymphoma, follicular lymphoma (FL) and chronic lymphocytic leukemia (CLL), as well as some T-cell lymphomas, breast cancer, lung cancer, ovarian cancer, and prostat a cancer.
