Name: ALDH1A1 (Polyclonal)
Description and applications: ALDH1 isoform A1, also known as retinal (acetaldehyde) dehydrogenase 1 or aldehyde dehydrogenase 1 (ALDH1) has the mission to convert / oxidize the retinaldehyde in retinoic acid and is codified by a gene on the chromosome region 9q21.13.1.This enzyme belongs to a family of evolutionarily highly conserved ALDH enzymes comprising 19 isoforms localized in the cytoplasm, mitochondria or the nucleus and are involved in the metabolism of aldehydes units, retinol, certain xenobiotic compounds and likewise are involved in ethanol oxidation and Ras GTPase activity. Low levels of cytosolic together with normal levels of mitochondrial ALDH it’s seen in patients with alcoholic fatty liver.
Composition: anti-human ALDH1A1 goat polyclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Immunogen: peptide mapping at the N-terminus of ALDH1A1 of human origin.