Name: Pan Melanoma Cocktail Antibody clone HMB45+M2-7C10+M2-9E3
Description and applications: The antibody represents a cocktail of anti-gp100 (HMB45) and MART-1 antibodies. By
immunohistochemistry, it recognizes melanocytes and melanomas. This cocktail reacts with junctional and blue nevus cells and with fetal and neonatal melanocytes. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. The antibody labels melanotic as well as amelanotic variants of melanomas. It is extremely sensitive for labeling formalin-fixed, paraffinembedded melanomas and other tumors showing melanocytic differentiation.
Composition: Anti-human Pan Melanoma Cocktail mouse monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide