آنتی بادی Cyclin D1 کلون CCND1/3370R برند Patho Sage

Specification:

Recognizes a protein of 36kDa, identified as Cyclin D1, one of the key cell cycle regulators, is a putative protooncogene overexpressed in 2 wide varieties of human neoplasms. This antibody neutralizes the activity of Cyclin D1 in vivo. About 60% og mantle cell lymphomas (MCL) contain at (11;14)(q13;32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas from CLL/SLL and follicular lymphomas. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Immunogen:

A synthetic peptide corresponding to residues within aa 270-295 of Cyclin D1

Presentation:

Bioreactor Concentrate with 0.05% Azide