Specification:
The catenin’s alpha, beta, and gamma are proteins which bind to the highly conserved, intracellular cytoplasmic tail of Ecadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Catenin, a 102 kDaprotein, was initially described as an E-cadherin-associated protein and has been shown to associate with other members of the cadherin family N-cadherin and P-cadherin. The 92 kDa catenin associates with the cytoplasmic portion of E-cadherin which is necessary for the function of E-cadherin as an adhesion molecule. Catenin has also been found in complexes with the tumor suppressor protein APC. Catenin, also known as plakoglobin, is an 82 kDa protein that binds with catenin and Ncadherin. A related protein, p120, exhibits sequence homology with the catenins at four discreet domains. p120 not only serves as a substrate for Src but is also found in E-cadherin complexes containing catenins. p120 (15D2): sc-23872. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tissue showing membrane and cytoplasmic localization.
Presentation:
Each vial contains 200 µg IgG in 1.0 ml of PBS with < 0.1% sodium azide 1 and 0.1% gelatin
دیدگاهها
هیچ دیدگاهی برای این محصول نوشته نشده است.