Name: Podoplanin Antibody Clone D2-40
Description and applications: D2-40 recognizes the M2A antigen encoded by the gene Prox1 localised on the chromosomal region 1q32.2–q32.3. It consists in a sialoglycoprotein of 40 kDa, containing mucin-type carbohydrate structure required to preserve the antigenicity of this molecule. M2A is expressed in lymphatic vessels and is absent in venous and arterial vascular endothelium. Other normal tissue that express Podoplanin are myoepithelial cell, mesothelial cells, dendritic cells, cells of the biliary ducts, osteocytes, chondrocytes, granulosa cells, squamous epithelium basal cells etc. It is expressed in various types of vascular tumors, seminomas and in some degree embryonal carcinomas, mesotheliomas, haemangioblastomas, schwanomas, dermatofibromas, thricoblastomas etc.
Composition: anti-Podoplanin mouse monoclonal antibody obtained from supernatant culture and prediluted in a tris buffered solution pH 7.4 containing 0.375mM sodium azide solution as bacteriostatic and bactericidal.
دیدگاهها
هیچ دیدگاهی برای این محصول نوشته نشده است.