Name: CD79a Antibody (Clone SP18)
Description and applications: A disulphide-linked heterodimer, consisting of CD79a/mb-1 and CD79b/B29 polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is an excellent marker of B cells and tumors derived therefrom, particularly useful for identifying infiltration by pre-B lymphomas and acute leukemias with intense plasmacytoid differentiation. T cell lymphomas and myeloid malignancies are consistently negative.
Composition: anti-human CD79a rabbit monoclonal antibody purified from ascites. Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Immunogen: Synthetic peptide derived from N-terminus region of human CD79a protein.
