Name: L1CAM Antibody clone BSR3
Description and applications:L1CAM (L1 cell adhesion molecule protein) is a cell adhesion molecule with an important role in the development of the nervous system. The L1, neural cell adhesion molecule (L1CAM) plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. L1 protein is expressed to tissues arising from neuroectoderm. L1CAM plays also an important role in the malignancy of human tumors and according to several studies, L1CAM positive carcinomas have a bad prognosis. L1CAM is overexpressed in many human carcinomas but it is useful especially in endometrium carcinoma diagnostic.
Composition : Anti-human L1CAM rabbit monoclonal antibody purified from culture supernatant, filtered, sterilized and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide
Intended use : Immunohistochemistry (IHC) on paraffin embedded tissues. Not tested on frozen tissues or Western-Blotting