Name: Melan A/Mart-1 Antibody Clone EP43
Description and applications: MART-1, also known as Melan-A,is a melanocyte lineage-specific protein (MART-1; melanoma antigen recognized by T cells 1) recognized by the T lymphocytes of patients with established malignancy. Antibody to MART-1 labels both normal melanocyte and diseased cell with melanocyte differentiation. It is useful for diagnosis of tumors with melanocyte differentiation, especially metastatic melanoma. Identification of MART-1 also opens possibilities for the development of immunotherapies for patients with melanoma.
Composition: Anti-human Melan A/Mart-1 rabbit monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide INTENDED USE Immunohistochemistry (IHC) on paraffin embedded tissues. Not tested on frozen
tissues or Western-Blotting.
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