آنتی بادی Cytokeratin 14 کلون LL002 برند Patho Sage

Specification:

Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and nonbasal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncolytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

Immunogen:

A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14

Presentation:

Bioreactor Concentrate with 0.05% Azide