آنتی بادی MBP (Myelin Basic Protein) کلون MBP/4277R برند Patho Sage

Specification:

Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin; it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the ‘’executive molecule of myelin’. MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin and clathrin and negatively charged lipids, and acquires structure on binding to them. It may acts as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocyte and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas

Immunogen:

Recombinant fragment (around aa 150-250) of human MBP (Exact sequence is proprietary)

Presentation:

Bioreactor Concentrate with 0.05% Azide