آنتی بادی P63 کلون TP63/1423 برند Patho Sage

Specification:

p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratin’s and the prostate-specific marker AMACR (P504S clone 13H4). p63 has also been shown to be sensitive marker for lung squamous cell carcinomas (SCC), with a sensitivity of ~90%. Specificity for lung SCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Immunogen:

Recombinant p63 protein.

Presentation:

Protein A/G purified antibody with 0.05% BSA & 0.05% azide.