Specification:
This antibody is designed for the specific localization of Vimentin in formalin-fixed, paraffin-embedded tissue sections. It is intended for in vitro diagnostic use. Vimentin is the major intermediate filament in a variety of mesenchymal or mesenchymally derived non-muscle cell types, including endothelial cells, all fibroblastic cells, macrophages, neuroblastomas, Sertoli cells, melanocytes, lymphocytes and ovarian granulosa cells. This antibody binds specifically to the 57 kD intermediate filament vimentin using immunoblotting. Vimentin is found in all types of sarcomas and lymphomas. Positive staining for vimentin is seen in most cells of fibrosarcomas, liposarcomas, malignant fibrous histocytomas, angiosarcomas, chondrosarcomas and lymphomas. When the vimentin antibody is used in combination with other antibodies as a panel, it can aid in the histological classification of normal and malignant tissues.
Presentation:
Mouse Monoclonal antibody in TBS, pH 7.6, containing 1% BSA and 0.09% sodium azide.
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