Clone | QR078 |
---|---|
REF | C-E005 |
Dilution | 1:100 – 1:200 |
Immunogen | Synthetic peptide of human EGFR |
Isotype | IgG |
Species of origin | Rabbit |
Epidermal growth factor is a growth factor that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. EGFR is a receptor tyrosine kinase activating several signaling cascades. It is ubiquitously expressed and observed in tumors of head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach, and in squamous cell carcinoma. Overexpression of EGFR in tumors indicates poor prognosis.