آنتی بادی مونوکلونال فلوسایتومتری CD14-FITC ، کلون MEM-15

Name: Flow Cytometry Antibody CD14-FITC, Clone MEM-15

• Antibody CD14-FITC is a monoclonal antibody (mAb) labelled with the tandem fluorescein isothiocyanate (FITC), designed for flow cytometry (FC) use as direct immunofluorescence reagent for the identification and enumeration of CD14 antigenexpressing cells.

SUMMARY AND EXPLANATION

• Leukocytes are named according to structure as being either granulocytes or agranulocytes, and according to the function as either phagocytes or immunocyte. The granulocytes, which include neutrophils, basophils and eosinophils, are all phagocytes. Of the agranulocytes, the monocytes and macrophages are phagocytes whereas the lymphocytes are immunocytes. Monocytes ingest dead or damaged cells and help defend against many infectious organisms. Anti-CD14 mAb recognizes CD14 antigen present on monocyte/macrophage cells. The reagent is important for excluding CD14+ monocytes in relation to T lymphocytes subsets analysis. In FC, anti-CD14 is considered essential for the initial evaluation of acute myeloid leukaemias together with a panel of other antibodies.

REAGENT COMPOSITION

The purified monoclonal CD14 antibody conjugated with tandem fluorescein isothiocyanate (FITC supplied in phosphate buffered saline with 0,09% sodium azide and 0,2% (w/v) bovine serum albumin (BSA).

• Clone: MEM-15
• Isotype: Mouse/IgG1.
• Amount per 1 ml vial: 200 determinations (5 µl/ Test).
• Reagent is considered non-sterile.