آنتی­ بادی Hepatocyte Specific Antigen (Hep Par 1) (OCH1E5)

Name: Hepatocyte Specific Antigen (Hep Par 1) Antibody (Clone OCH1E5)

Description and applications: Anti-hepatocyte specific antigen, also known as anti-Hep-Par1, recognizes both benign and malignant liver-derived tissues including such tumors as hepatoblastoma, hepatocellular carcinoma (including its fibrolamellar variant), and hepatic adenoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in differentiating hepatocellular carcinomas with adenoid features from adenocarcinomas, either primary in the liver or metastatic lesions to the liver. In labeling hepatoblastoma, it is useful in differentiating this entity from other small round cell tumors. No reaction is usually seen with other human tumors with the exception of some gastrointestinal tumors. Occasionally it might be expressed by some tumors which include adrenal carcinomas, yolk sac tumors, adenocarcinomas of the colon, lung, ovarian carcinomas and adenocarcinomas of the endocervix.

Composition: anti-human HepPar 1 mouse monoclonal antibody purified from ascites. Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.