Specification:
C-erbB2 (also called Her-2/neu, ERBB2 or neu) is a transmembrane receptor tyrosine kinase. HER-2 is considered as the target oncogene driving the amplification, so that its activation will causes malignant transformation and increases the malignant potential (cell proliferation, invasiveness etc.) of the cells. Amplification of C-erbB2 gene invariably leads to overexpression of its protein product. Over-expressed C-erbB protein disturbs the HER-receptor family signaling networks, i.e. signaling mediated via EGFR receptor.
Presentation:
Supernatant contains 15mM sodium Azide
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