آنتی بادی C-erbB-2 (HER2) کلون MXR011 برند Patho Sage

Specification:

C-erbB2 (also called Her-2/neu, ERBB2 or neu) is a transmembrane receptor tyrosine kinase. HER-2 is considered as the target oncogene driving the amplification, so that its activation will causes malignant transformation and increases the malignant potential (cell proliferation, invasiveness etc.) of the cells. Amplification of C-erbB2 gene invariably leads to overexpression of its protein product. Over-expressed C-erbB protein disturbs the HER-receptor family signaling networks, i.e. signaling mediated via EGFR receptor.

Presentation:

Supernatant contains 15mM sodium Azide