Name: Mouse anti-human Tartrate-Resistant Acid Phosphatase (TRAcP) Monoclonal Antibody (Clone 9C5)
Description and applications: Tartrate-resistant acid phosphatase (TRAcP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher’s disease; spleen of patients with Hodgkin’s lymphoma and in the sera of patients undergoing active bone turnover.
The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades. Anti-TRAcP antibody labels the cells of hairy cell leukemia (HCL) with a high degree of sensitivity and specificity.
Composition: anti-human TRAcP mouse monoclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.