| Clone | QR007 |
|---|---|
| REF | C-P004 |
| Dilution | 1:100 – 1:200 |
| Immunogen | Synthetic peptide of human p63 |
| Isotype | IgG |
| Species of origin | Rabbit |
p63 is a transcription factor with significant structural similarity to p53 and p73. p63 plays a critical role in the growth and development of many epithelial organs.
p63 is highest expressed in squamous cell carcinoma irrespective of their origin (96-100%). Anti-p63 may be useful in the detection of squamous cell carcinoma of the head and neck (HNSCC), of the lung and skin. Prostate adenocarcinoma is almost always p63 negative, so p63 is used for the differentiation between prostate adenocarcinoma and benign prostate tissue.
