Name: Cytokeratin 14 antibody clone LL002
Description and aplications: Cytokeratin 14 belongs to the type A (acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5. Cytokeratin 14 has been studied as a prognostic marker in breast cancer. Here it is used as a marker for the myoepithelial cells and for the identification of basaloid histotype of breast carcinoma.
The antibody also distinguishes stratified epithelial cells from simple epithelial cells and has been reported useful in the identification of squamous cell carcinomas.
Composition: anti-human Cytokeratin 14 mouse monoclonal antibody purified from ascites fluid by Protein G chromatography. Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide
Immunogen: A synthetic peptide of 15 amino acid residues from the C-terminus of human keratin 14.